Meeting/Event Information

    Stieglitz Lecture with University of Chicago: Prof. Laura Kiessling (UW-Madison) "Us Versus Them: Distinguishing Host and Microbial Cells with Glycans"

    February 12, 2015
    5:00 PM - 9:30 PM
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    Gordon Center for Integrative Science, University of Chicago
    929 E. 57th St.
    Chicago, IL 60637
    http://ibd.uchicago.edu/index.shtml
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    The 2014/15 Stieglitz Lecture

    Julius Stieglitz with signaturePlease join the Chicago Section ACS and the University of Chicago for a prestigious lecture of historic significance. Bringing together the University of Chicago and the Chicago Section of the ACS at the university's home, we fulfill the legacy of Prof. Julius Stieglitz, who was strongly tied to both institutions: Chemistry Dept. Chair 1915-1933, Chicago ACS Chair 1904, ACS President 1917, ACS Chair 1933. Our present Stieglitz Lecturer, Prof. Laura Kiessling, is one of the leaders in the field of chemical biology, and her work is well aligned with Prof. Stieglitz' research interests, organic and medicinal chemistry. The Stieglitz Lecture began in 1940 as a joint enterprise between our institutions, and previous Stieglitz Lecturers include Linus Pauling, Carl Djerassi, Henry Lardy, Frank Westheimer, Sam Danishevsky, and many other leading lights. We hope you enjoy this year's lecture by Laura Kiessling and share the company of chemists from the UofC and the Chicago Section at the social hour and dinner.

    ABSTRACT

    All cells are covered with a coat of glycans, yet the glycans on mammalian cells can differ markedly from those on microbial surfaces. In principle, these differences in glycosylation could be exploited. Specifically, agents that selectively block the biosynthetic enzymes found only in microbes would serve as new antimicrobial leads. Moreover, glycan differences could be used by host carbohydrate-binding proteins or lectins to distinguish themselves from their microbial guests. We are exploring how the cell surface carbohydrate coat of microbes is built and how it can be detected by human lectins. This seminar will focus on these topics and their implications for the human immune system and for devising new anti-microbial therapies.

    PROGRAM

    • 5:00 - 6:30  Registration & Social Hour with cash bar
    • 6:30 - 6:35  Introductory remarks by Inessa Miller, 2015 Chicago ACS Chair
    • 6:35 - 6:45  Julius Stieglitz and the Stieglitz Lecture - Josh Kurutz, Stieglitz Committee Chair
    • 6:45 - 7:45  Stieglitz Lecture by Prof. Kiessling
    • 8:00 -          Dinner in the GCIS atrium

    BUFFET MENU: 

    • Bruschetta Chicken Grilled Chicken Breast topped with Chopped Tomatoes, Onions, Fresh Basil and Feta Cheese Drizzled with a Light Balsamic Sauce  
    • Pasta Primavera Fresh Penne Pasta Sautéed with Squash, Zucchini, Onions and Cherry Tomatoes Tossed in a light white wine sauce and topped with parmesan cheese  
    • Green Beans Almandine Steamed green Beans tossed with Sliced Almonds and a Light Lemon Butter Sauce  
    • Harvest Field Green Salad Field Greens, Dried Cranberries, Sliced Apples, Crumbled Blue Cheese and balsamic Vinaigrette  
    • Dinner Roll Basket  
    • Dessert Display Mini Assorted Cookies Brownie Bites Fresh Fruit Tarts Cheesecake Bites   
    • Beverages: Bottled Water Assorted Canned Soda

    UofC map thumbnailMAP and PARKING:

    Click here for a map of the campus that highlights the location of the meeting and nearby parking.

    Recommended parking is in the paid lot at the corner of 55th and Ellis Ave., near undergraduate dorms and the Smart Museum.

    The main entrance of the GCIS is in a large breezeway at 927 E. 57th St., Chicago, IL, 60637, and features a loading zone. The meeting will be on the third floor, and signs will be posted to provide directions.

    BIOGRAPHY: Prof. Laura Kiessling

    Laura received her undergraduate training in Chemistry at the Massachusetts Institute of Technology. There she conducted undergraduate research in organic synthesis with Professor Bill Roush. She received her Ph.D. in Chemistry from Yale University where she worked with Stuart L. Schreiber on the synthesis of anti-tumor natural products. Her postdoctoral training at the California Institute of Technology in the research group of Peter B. Dervan led her to explore the recognition of duplex DNA through triple helix formation. She began her independent career in the Department of Chemistry at the University of Wisconsin-Madison in 1991.

    She is a member of the American Academy of Arts & Sciences, the American Academy of Microbiology, and National Academy of Sciences. Laura's honors and awards include a Guggenheim Fellowship, an ACS Frances P. Garvan-John M. Olin Medal, a Harrison-Howe Award, an Arthur C. Cope Scholar Award, the Hudson Award in Carbohydrate Chemistry, the Alfred Bader Award in Bioorganic or Bioinorganic Chemistry, and a MacArthur Foundation Fellowship. She is also the founding editor-in-chief of ACS Chemical Biology.

    Her interdisciplinary research interests focus on elucidating and exploiting the mechanisms of cell surface recognition processes, especially those involving protein-glycan interactions. Another major research interest is multivalency and its role in recognition, signal transduction, and direction of cell fate.

     

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    Tickets

    $10.00 Tote bag: CHICAgO elements - natural canvas

    $10.00 Tote bag: CHICAgO elements - blue

    $0.00 Lecture only