Meeting/Event Information

    Translating Basic Science into Products & the Role of Diversity - Prof. Joseph DeSimone, UNC (Stieglitz Lecture)

    November 07, 2012
    5:00 PM - 9:30 PM
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    Holiday Inn - Elk Grove Village
    1000 Busse Road
    Elk Grove Village, IL 60007
    http://www.hielkgrove.com
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    Can the technology behind improving computer chip speed also help manufacture better medicines? This lecture will describe the insights, the team and the strategies behind translating the basic science and engineering from one industry (microelectronics) into products useful in other fields (medicine and vaccines) to improve the health and well-being of society.

    Please join the Chicago ACS and the University of Chicago for the 2012 Stieglitz Award Lecture and Reception, featuring awardee Dr. Joseph DeSimone (Chancellor's Eminent Professor of Chemistry at the Univ. of North Carolina & William R. Kenan, Jr. Distinguished Professor of Chemical Engineering at North Carolina State University, Raleigh, & Director of the Frank Hawkings Kenan Institute of Private Enterprise at UNC-Charlotte).

    PRE-Dinner speaker: Dr. Anita Mehta, CEO of Chicago Discovery Solutions, will present "In Search of Blockbusters for Increasing Good Cholesterol With Ester Transfer Protein Inhibitors"

    PROGRAM

    5:00 - 6:00 PM · Job Club
    5:30 - 6:15 PM · Pre-dinner talk (Mehta)
    5:30 · 6:30 PM · Social Hour
    6:30 - 7:30 PM · Dinner 
    7:30 -          PM · General Meeting, including talk (DeSimone)

    ABSTRACT (main talk)

    In 1965, Gordon Moore, co-founder of Intel, described the trend that the number of components in integrated circuits had doubled every year since 1958. This trend has continued to today, enabled by advances in photolithography which has taken the minimum feature size of transistors down from about 10 microns in 1970 to 0.045 microns (45 nm) today. In biological terms, this corresponds to going from the size of a red blood cell to the size of a single virus particle! As such, this top-down nano-fabrication technology from the semiconductor industry is, for the first time, in the size range to be relevant for the design of medicines, vaccines and interfacially active Janus particles. 

    ABSTRACT (pre-dinner talk)

    A search for drugs to increase good cholesterol has been a long sought after goal. The first CETP inhibitor, torcetrapib was unsuccessful because it increased levels of the hormone aldosterone and increased blood pressure, which led to excess cardiac events when it was studied. Recently, Roche stopped development on its CETP inhibitor dalcetrapib, a drug designed to raise HDL cholesterol in the blood. The developers of CETP inhibitors assume that raising HDL levels correlates with a lowering of cardiovascular risk and should give blockbuster drugs like Statins.The talk will focus on the evolution of the CETP inhibitors and updates on new advanced clinical candidates hoping to make it to the market.

    DINNER

    Fresh Fruit Cup
    Soup Du Jour
    Tossed Salad with Choice of Dressing

    ENTRÉE CHOICE:

    • Beef Prime Rib
    • Blackened Tilapia
    • Pasta Primavera

    Vegetable and Starch 
    Dessert

    BIOGRAPHY:   We are pleased to welcome Dr. DeSimone as our Stieglitz Lecturer for 2012. We are fortunate to have a chemist of such honor and achievement as our speaker for this evening.  If you view his resumé, it is easy to see why the honors have come. First, his work has taken place in those areas which are at the forefront of our society’s technical needs and interests: computers, nanotechnology, and medical technology, to name several prominent areas. Second, his work has been successful in serving as a bridge at a time when there is a need to merge the research and development findings from science and engineering to create new and more efficient techniques and products. Dr. DeSimone has certainly been prominent as a leader in this regard.

    Joe received his B.S. in chemistry from Ursinus College in Collegeville, PA, near Philadelphia, in 1986, followed by his Ph.D. in chemistry from Virginia Polytechnic and State University in Blackburg, VA in 1990 with Dr. James E. McGrath as his advisor.   We can see how successful he has been in carrying out this work by the manner and number of his awards and recognitions. They have come equally from the technical as well as the social sides of our society.

    Dr. DeSimone has been very active and creative in the various areas of his work and in areas of leadership for his university. This is reflected by his appointments in the many leadership roles for his University. This is also reflected by his achievements in being recognized as a Named Professor of Chemistry at UNC and as a Distinguished Professor of Chemical Engineering at NC State. Just recently he was appointed Director of the Frank Hawkins Kenan Institute of Private Enterprise, a business institute for the UNC campus.

    He has published nearly three hundred papers in various intellectual and scholarly areas of his work and has received 135 domestic and foreign patents. He has received awards and recognitions from many different donors honoring his work. A few of them are listed below as representative of his works. He is a great teacher and has been responsible for many students as postdocs, graduate students, and undergraduates who have worked in his labs.

    Tickets

    $37.00 Member

    $39.00 Non-member

    $20.00 Student/Unemployed/Retired

    $0.00 Cash at the door: $35 member/ $37 nonmember/ $20 student/retired/unemployed